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Analysis of the Activation of the Nrf2-ARE Pathway Following Optic Nerve Injury in Mice

   
@article{YKXB3666,
	author = {Feng Yan 和 Suihua Chen 和 Xiangjun Ji 和 Chuang Nie 和 Hainan Xie},
	title = {Analysis of the Activation of the Nrf2-ARE Pathway Following Optic Nerve Injury in Mice},
	journal = {眼科学报},
	volume = {27},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {Purpose:The Nrf2-ARE pathway plays a cytoprotective role in many tissues,but its protective function in the optic nerve is unclear. The purpose of the study is to investigate the changes in activation of the Nrf2-ARE pathway following optic nerve injury (ONI) in mice. Methods:Using ONI mice models,the expression levels of Nrf2 in optic nerves were determined by real-time PCR at various time points. Results:The expression of Nrf2mRNA was significantly up-regulated at 1 d after ONI, peaking at 30 min after ONI. Conclusion:The Nrf2-ARE pathway was activated after ONI, providing evidence for the study of the protection and underlying mechanism of Nrf2-ARE pathway on optic nerves.},
	url = {https://ykxb.amegroups.com/article/view/3666}
}