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Correlation of polymorphism of MMP-3 gene with the risk of type 2 diabetic retinopathy

   
@article{YKXB3865,
	author = {Jie Yang 和 Tiemin Zhang 和 Xiucheng Cui 和 Yinghui Ma 和 Hongmei Wang},
	title = {Correlation of polymorphism of  MMP-3  gene with the risk of type 2 diabetic retinopathy},
	journal = {眼科学报},
	volume = {31},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Objective: To determine the correlation between polymorphism at MMP-3 gene and risk of type 2 diabetic retinopathy (DR). 
Methods:In a hospital-based case-control study, MMP-3 SNP was genotyped by polymerase chain reaction-restrictive fragment length polymorphism (PCR-RFLP) analysis in 195 diabetic retinopathy patients, 205 diabetes mellitus patients and 261 healthy persons as control. 
Results: There is no significant difference between the Control groups, DM group and DR group in allele or genotype distributions of MMP-3-1171 5A/6A (P=0.474 and P=0.407). There is no significant difference between the NPDR and PDR group in allele or genotype distributions of MMP-3-1171 5A/6A (P=0.724 and P=0.820). 
Conclusion: There is no significant difference between the Control groups, DM group and DRgroup in allele or genotype distributions of MMP-3 -1171 5A/6A.},
	url = {https://ykxb.amegroups.com/article/view/3865}
}