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In vitro eye embryogenesis from induced pluripotent stem cells for ocular surface disease treatment

   
@article{YKXB3892,
	author = {Matthias Fuest 和 Jodhbir S. Mehta},
	title = {In vitro eye embryogenesis from induced pluripotent stem cells for ocular surface disease treatment},
	journal = {眼科学报},
	volume = {31},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {In their letter to Nature, Hayashi et al. describe a new method for the generation of ocular surface epithelium-like cells by incubating human induced pluripotent stem cells (iPS) into four defined concentric zones mimicking the developing eye, which the authors named as self-formed ectodermal autonomous multi-zone (SEAM) (1). Different SEAM zones contained cells with characteristics of the ocular surface ectoderm, the lens, the neural retina and the retinal pigment epithelium. Isolated corneal surface-like cells successfully reinstated a corneal epithelium in a rabbit limbal stem cell deficiency (LSCD) model. The paper offers a new option for patients with LSCD.},
	url = {https://ykxb.amegroups.com/article/view/3892}
}