Pathological Changes in Rabbit Retina and Its Relationship with Glutamic Acid after Injuries from High-Speed Bullets
摘要
Purpose:To observe the pathological changes in rabbit retinas and the measure of glutamic acid levels in the vitreous body after suffering from high-speed bullet injuries.Methods:Rabbits eyeball contusion models were established with high-speed bullets,i.e,the rabbits eyes were shot with a fixed air rifle at a speed of 90 m/s.(using plastic bullets,weighing 0.201 g,on average).Retinal tissues treated with HE staining and were prepared for light microscopy examination and glutamate levels were tested at different time points after the injury.Results:Edema,exudation,hemorrhage,and rupture were evident in rabbit retinas following bullet injuries.Meanwhile,glutamate levels gradually increased as time proceeded.Conclusion:Visual impairment is related with retinal damages after high-speed bullet injuries.Increased glutamate concentration serves as a potential factor for aggravating retinal injuries.
